Red Vine Leaf Extract, Vitamin C (as Ascorbic Acid), Capsule Shell (Hydroxypropyl Cellulose), Grapeseed Extract, Bulking Agent (Microcrystalline Cellulose), Anti-Caking Agents (Magnesium Stearate, Silicon Dioxide). Antioxidants in red vine leaves help protect cells and DNA from damage buildup caused by free radicals and prevent them from altering normal cell activity that could turn regular cells into cancerous ones. Free radical damage buildup, known as oxidative stress, causes extensive inflammation which is a risk factor for chronic disease. A 2012 Japanese study revealed that red vine leaves extract holds anti-inflammatory effects and may contribute to reducing liver damage. No AI tool has the depth of experience accumulated over tens of thousands of sessions with real human beings (in fact, AI tools have zero experience, obviously). Neither can an AI tool discriminate what is reality and what is made up BS on the web. Prices and special offers: Subject to change without prior notice. Special offers can not be combined. Although the red vine leaf extract studies were small in number, the available evidence suggests that AS 195 has properties that may help to maintain healthy leg-vein function. As such, its role in the prevention of CVI and in ameliorating established venous disease could be further explored. Such investigations may include evaluation of the correction of early vein changes to prevent venous ulceration and the role of red vine leaf extract in maintaining leg-vein integrity, thus leading to enhanced treatment options and a recurrence-prevention strategy.

The overall result of this is the quality of life for the person suffering from either CVI or varicose veins is rapidly improved. Eladiet offers us Red Vine in tablets, a supplement that helps maintain normal circulation. In herbal medicine, the red vine is known primarily for its benefits on the bloodstream. Recent studies have investigated the action of flavonoids in preventing atherosclerotic plaques (Hollman and Katan, 1997). Bioflavonoids or flavonoids are a class of water-soluble substances found in a number of plants or plant-derived products. It is believed that flavonoids have a wide range of beneficial effects when taken in the diet, including anti-inflammatory, antihistaminic and antiviral action. Formica and Regelson (1995) concluded that flavonoids are important in the maintenance of capillary wall integrity and resistance.A cooling leg gel containing red vine leaf extracts that is designed to soothe and refresh tired, heavy legs, is also available. Leach, M.J. (2004) Making sense of the venous leg ulcer debate: a literature review. Journal of Wound Care; 13: 4, 52-56. Drug therapy is a treatment option in incipient and mild to moderate CVI. Leach’s (2004) review of leg ulceration included the evidence for systemic therapy, namely orally administered phlebotonic (venotonic) agents. Such drugs are often plant-derived substances for which an anti-exudative (anti-inflammatory) and anti-oedematous action and efficacy have been confirmed in experimental studies and clinical trials. Experimentally, most have a membrane-stabilising action, leading to a decrease in capillary permeability. Some also have antioxidant properties. An esvs Journal study conducted in 2011 found that AS195 led to an improvement in the clinical profile of patients with CVI, and that swelling and pain in the leg were significantly reduced. The phytonutrients present in its leaves act as natural venotonics, angioprotectors and anti-edematous. In other words, they contribute to the tonicity and protection of blood vessels and capillaries. They are particularly capable of reducing the permeability of blood vessels and improving their resistance. Therefore, a red vine treatment may be of interest to combat venous insufficiency, to alleviate the sensation of heavy and / or swollen legs, among other benefits.

Common symptoms include fat accumulation, oedema (water retention), heavy legs, muscle cramps, pain, varicose veins and cellulite. The leaves have the same resveratrol properties as the wine, but in addition to this they have a vast array of other health properties, including protective polyphenols and anthocyanins. In recent studies it has been proven to be an effective remedy for the effects that come as a result of CVI and varicose veins. This is what makes it a useful bath for the legs, especially for someone that spends their whole day on their feet. The effects such as tired legs were also remarkably improved as a result of using red vine leaf extracts. The product was therefore shown to be effective even when used for a short while. Red Vine Leaf Extract BenefitsThe leaves of the grape vine (Vitis vinifera) are an increasingly popular culinary vegetable, used in a variety of recipes from cuisines around the world. But more important, vine leaves are an excellent source of powerful antioxidant compounds with impressive health effects. The red vine leaf, in particular, has been found to help improve conditions related to poor blood circulation, notably varicose veins and associated symptoms. Antioxidants in general exhibit anti-inflammatory properties as well and can help reduce swelling and pain associated with inflammatory conditions. These biological active compounds also exert antimicrobial effects. A 2011 study from the International Journal of Food Properties revealed that red vine leaves hold strong antimicrobial properties against Staphylococcus aureus, Escherichia coli and Salmonella Infantis ( Phenolic Profile, Antioxidant Capacity, and Antimicrobial Activity of Leaf Extracts from Six Vitis vinifera L. Varieties). Physical mobilisation, avoidance of prolonged sitting or standing, and elevation of the legs reduce the venous pressure and facilitate venous return in the affected areas. Treatment centres around the application of external pressure to the limb to mechanically splint the vessels, preventing their distortion and engorgement by the physical narrowing of blood vessel lumen. In this way, faulty valves can be supported and intravessel blood velocity increased (Oduncu et al, 2004). Numerous studies report that the antioxidants in red vine leaves and the subsequent red vine leaf extract are efficient for the treatment of varicose veins, also known as chronic venous insufficiency. The extract has successfully been used in clinical trials to prevent edema (swelling) and other symptoms associated with the condition. Following a 42-day study, subjects reported an improvement in symptoms such as: tiredness and fatigue, pain, tingling and tension sensation in the legs ( Oedema protective properties of the red vine leaf extract AS 195 (Folia vitis viniferae) in the treatment of chronic venous insufficiency. A 6-week observational clinical trial).

Research paper abstract: “Aim: Chronic venous insufficiency (CVI) is common in adults. Some complications include skin changes, edema, heavy legs, muscle cramps, pain, and varicose veins. In traditional medicine, red vine leaf extract (AS 195) has been used to cure the symptoms of CVI. This systematic review was aimed to assess the effects of AS 195 in patients with CVI. Material and methods: A systematic literature search was performed to identify trials that reported the impact of red vine leaf extract on CVI. The primary outcomes investigated were Leg (limb) volume, calf circumference, ankle circumference, tired and heavy legs, a sensation of tension, tingling sensation, and pain. Results: From the 56 studies, 5 trials were selected according to our inclusion criteria. Red vine leaf extract significantly improved numbers of outcomes (lower leg volume, calf and ankle circumference, tired, heavy legs, tingling sensation, pain, the sensation of tension in the legs, cutaneous microcirculation, and transcutaneous oxygen pressure) in only some trials. The tolerability for red vine leaf extract was reported good or satisfactory. Conclusions: Red vine leaf extract had a beneficial therapeutic role in patients with CVI. Further high‐quality trials are required to be carried out to provide strong evidence.“There are dozens of studies on the effects of red vine leaf extract, a natural traditional medicine used to treat symptoms of CVI in Continental Europe for several decades The usual dose is 360 mg to 720 mg daily, but follow manufacturer’s instructions as the concentration of red vine leaf extracts vary. Only select supplements made to a pharmaceutical standard known as GMP, as low quality red vine leaf products (on sale in health food shops in Japan) were found to contain low levels of active polyphenols, and inconsistent levels per tablet. Red vine leaf extracts stabilise the endothelial lining of tiny capillaries and promote their repair and reduce their permeability. This makes capillaries less leaky so less fluid passes from the circulation into the tissues to cause swelling of (oedema) of surrounding tissues. It has been observed that French wine farmers don’t get chronic venous insufficiency (CVI), mainly because they take a red vine leaf extract that contains large amounts of bioflavonoids like quercetin, quercitrin and kaempherol. In fact, a commercial extract (AS 195) of red vine leaf has been available for some time.